Monday, September 24, 2012

Loving the seasons

Rain today in Utah, But the leaves on the mountains are beautiful!!
From almost anywhere in the valley you are surrounded by a blend of earth tones... leaves in orange, yellow, red. Amazing

Thursday, September 20, 2012

Limitless Worldwide LLC Event at the Hilton downtown Salt Lake City, Utah

What a great event!!





Sigman Group Alumni- Amy Heaton Utah

Sigman Group Alumni
Graduate Students:
Keith Gligorich 
(Ph.D. 2009)
 Postdoctoral Fellowship with Bryan E. Welm
University of Utah, Huntsman Cancer Institute
keith.gligorich@hci.utah.edu
 
 
Candace Cornell 
(Ph.D. 2007)
 Moving to Seattle
cornell@chem.utah.edu
 
 
Ben Dible 
(Ph.D. 2006)
 Postdoctoral Fellowship with Patrick Holland 
University of Rochester
bdible@mail.rochester.edu
 
 
Mitchell Schultz 
(Ph.D. 2006)
 Research Scientist 
Bristol-Myers Squibb
mitchell.schultz@bms.com
 
 
Greg Mercer
(Ph.D. 2006)
 Senior Research Scientist
Albany Molecular Research, Rensselaer, NY
gregory.mercer@amriglobal.com
 
 
Sridhar Rajaram
(Ph.D. 2005)
 Postdoctoral Fellowship with Jean Frechet
University of California Berkeley 
sridharr@berkeley.edu
 
 
Jaime Mueller
(Ph.D. 2005)
 Assistant Professor of Chemistry
Saint Mary's University of Minnesota
jmueller@smumn.edu
 
 
David Jensen
(Ph.D. 2004)
 Senior Scientist
Nektar Therapeutics, Huntsville, AL
djensen@nektar.com
 
 
Ryan Adler
(M.S. 2004)
 Scientist
Tandem Labs, Salt Lake City, UT
Ryan.Adler@tandemlabs.com
 
 
Undergraduates:
Carol Bills
(2008)
 Undergraduate
University of Utah
 
Karisa Snow
(2008)
 Undergraduate
University of Utah
 
Dennis Poth 
(2007)
 Student at TU Braunschweig
Braunschweig, Germany
dennispoth@web.de
 
 
Sebastian Herbrich 
(2006)
 Student at TU Braunschweig
Braunschweig, Germany
s.herbrich@gmx.net
 
 
Laura Cotter 
(2006)
 Undergraduate
University of Utah
 
Kara Stowers
(2005-2006)
 Graduate Student in the Sanford Group
University of Michigan
kstowers@umich.edu
 
 
Matthew Weinstock
(2005)
 Graduate Student in the Biological Chemistry Department 
University of Utah
 
 
Cornelia Pfaffenroth
(2004)
 M.S. Student at TU Braunschweig
Braunschweig, Germany
 
Steve Hamilton
(2003-2004)
 Medical Student at the Mayo Clinic
Rochester, MN
Hamilton.Steven@mayo.edu
 
 
Amy Heaton 
(2003-2004)
 Graduate Student in the Armentrout Group
University of Utah
heaton@chem.utah.edu
 
 
Chris Goller
(2003-2004)
 Magpie Systems Inc.
Salt Lake City, UT
goller@gmail.com
 
 
Megan Sturdy 
(2003-2004)
 Graduate Student in the Medicinal Chemistry Department 
University of Illinois at Chicago
 
 
Justin Litchfield
(2002-2003)
 Graduate Student in the Du Bois Group
Stanford University
litch@stanford.edu
 
 
Candice Park 
(2000-2001)
 M.D. Residency Program
Arizona
 
Jacob Pugsley
(2000-2001)
 M.D. 
 
Dennis Hobuss 
(2000)
 Graduate Student in the Laschat Group
Universität Stuttgart
Stuttgart, Germany
 
 
Research Experience for Undergraduate Students:
Drew Camelio
(2008)
 Undergraduate
SUNY Oswego
 
Rajan Pragani
(2002)
 Graduate Student in the Vedejs Group 
University of Michigan
 
Abril Estrada
(2001)
 Graduate Student in the Waite Group 
University of California, Santa Barbara
 
Postdoctoral Scholars:
Dr. Sarah Cummings
(2006-2007)
 Lecturer and Organic Chemistry Coordinator
Department of Chemistry
University of Nevada, Reno
sac@unr.edu
 
 
Dr. Yang Zhang
(2006-2007)
 Principle Scientist 
Pharmatechs 
Shanghai, China 
yang_zhang@pharmatechs.com
 
 
Dr. Amy Balija
(2005-2006)
 
Visiting Assistant Professor
Fordham University (Rose Hill Campus)
wchemist@gmail.com
 
 
Dr. Maryann Endoma
Visiting Professor (2005-2006)
 Faculty
University of Philippines
Diliman, Quezon City
 
Dr. Jae-Young Lee
(2003-2004)
 Researcher
Department of Chemistry
Kangwon National University, Korea
 
 
Dr. Sunil Mandal 
(2002-2003)
 Sr. Scientific Manager
Biocon-Bristol-Myers Squibb R & D center (BBRC)
Syngene International Ltd
Bangalore, India
sunilkumar.mandal@syngeneintl.com
 

Speaking on Stage in Salt Lake City Utah

Speaking to the Science beyond the Testimonials in Basic Research/ Limitless Worldwide LLC headquarters.... Both Before I go on stage & on stage

Dr. Amy Heaton PhD


Amy Heaton - Utah Days

Amy L. Heaton
Graduate Student
  



Ph.D. Recipient
Department of Chemistry 
University of Utah
ayamie@gmail.com
  
MSPIRE Research Interests 
Heaton’s MSPIRE research used the free electron laser for infrared experiments (FELIX) facility at FOM ”Rijnhuizen” to measure infrared multiple photon dissociation (IRMPD) action spectra of metallated asparagine. Amy studied M+(Asn) complexes where M+ = H+, Li+, Na+, K, Rb+, Cs+., and Ba2+. Accurate quantum chemical calculations on these systems allow the conformations involved to be identified. The results demonstrate that the heavier alkali metals exhibit multiple conformers, whereas the lighter alkali metals and hydrogen have only a tridentate configuration. For the barium complex, in contrast to all other amino acids which have zwitterionic structures when complexed to Ba2+, Ba2+(Asn) exhibits only a charge-solvated tridentate conformation. 

In her Ph.D. studies, Heaton examined the interactions of alkali metal cations with a range of small biologically relevant molecules. Notably she used threshold collision induced dissociation (TCID) in a guided ion beam tandem mass spectrometer to measure the binding energies of Na and K+ with aspartic acid (Asp), asparagine (Asn), glutamic acid (Glu), and glutamine (Gln), determining several interesting trends in this thermochemistry. In addition, she has characterized both experimentally and theoretically the deamidation of Asn upon collisional activation of Na+(Asn) and H+(Asn). Additional studies include the binding of Na+ to simple sugars as measured using TCID as well as Rb+ to several amino acids. 

Heaton received her Ph.D. in chemistry from the University of Utah in 2009. She is currently working at Basic Research, Salt Lake City, UT. 

figure

Figure. The IRMPD spectra of H+(Asn), Cs+(Asn), and Ba2+(Asn) complex show distinct behavior.

image